Outflow tract ventricular tachycardias (OTVT) are the most common cause of idiopathic ventricular tachycardias followed by fascicular tachycardias
Structural heart disease must be ruled out as OTVT tachycardias can manifest in patients with underlying heart disease such as myocardial infarction, arrhythmogenic cardiomyopathy or sarcoidosis
In the absence of structural heart disease the prognosis is good
Management of OTVT differs in RVOT and LVOT tachycardias
The region of outflow tracts is anatomically complex and many structures can give rise to arrhythmias and precise determination of the origin may be possible only during electrophysiological study
two types of OTVT can be distinguished: - Paroxysmal OTVT is typically triggered by exercise or stress - Repetitive monomorphic OTVT usually occurs at rest and presents with runs of nonsustained VTs interrupted by sinus beats
Left ventricular outflow tract VT
LVOT VTs account for about 10-15% of idiopathic VTs
LVOT origin can be divided into more precise localisation including the aorto-mitral continuity (AMC), the anterior site around the mitral annulus (MA), the aortic sinus cusps (ASC), and the epicardium although these localisations are sometimes considered separately
All of these sites of origin exhibit similar morphology due to their close anatomical proximity
There are algorithms that can be used to precisely localise the origin of LVOT VT/PVC and it can be used in the decision to perform a catheter ablation as not all of the mentioned localisations can be successfully ablated.
LVOT VT is suggested by LBBB morphology with inferior axis with small R-waves in V1 and early precordial transition (R/S = 1 by V2 or V3) or RBBB morphology with inferior axis and presence of S-wave in V6.
inferior axis (positive deflections in leads II, III and aVF).
Aortic sinus cusp origin is sometimes difficult to differentiate from RVOT VT because both are so close to each other. Coronary cusp origin has to be thought when we fail an ablation in the RVOT, ECG shows a LBBB inferior axis morphology with taller monophasic R-waves in inferior leads and an early precordial R-wave transition by V2-V3.
if stable, utilize vagal maneuvers, adenosine, and/or verapamil
chronic therapy involves beta blockers, non-dihydropyridines, class IC agents (sodium channel blockers)
Curative catheter ablation should be considered, however, success rate of catheter ablation is lower than in the case RVOT VT/PVC and can have major complications and should therefore be performed only in highly experienced centres
ECG 1 Trigeminy of PVCs from commissure of right and left aortic cusps (curative ablation done)
ECG 2 Bigeminy originating from LVOT (curative ablation done)
bigeminy with PVCs of RBBB morphology in V1
inferior axis (positive deflection in leads II, III and aVF)
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